Location:
Wei SHI, Ph.D.
Professor
School of Environment
Nanjing University
Email: [email protected]
ORCID: 0000-0002-6263-5664
Education
2007.9-2011.6 Nanjing University, Environmental Chemistry, D.Sc
2003.9-2007.6 Nanjing University, Environmental Science, B.S.
Professional Experience
2019.12- Nanjing University, School of Environment, Professor
2014.6-2019.12 Nanjing University, School of Environment, Associate Prof.
2015.8-2016.8 University of California, Riverside, USA, Visiting scholar
2011.8-2014.6 Nanjing University, School of Environment,
Research Associate
Research Interests
1. Migration, transformation and toxic effects of organic pollutants in environmental processes
2. High throughput screening and risk assessment of chemicals / new pollutants
3. Classification, identification and traceability of toxic pollutants
Academic Service
Editorial board of Environmental Chemistry and Science of the Total Environment
Editor of Environmental Pollution special issue
Member of China Computational Toxicology Committee
Teaching
Chemical Risk Assessment
Organic Chemistry
Selected Publications
1. Tan H, Wang X, Hong H, Benfenati E, Giesy J P, Gini G, Kusko R, Zhang X, Yu H, Wei S, Guo J, Shi W*. Structures of endocrine-disrupting chemicals determine binding to and activation of the estrogen receptor α and androgen receptor, Environmental Science & Technology, 54: 11424−11433(2020)
2. Chen Q, Wang X, Tan H, Shi W*, Zhang X, Wei S, Giesy J P, Yu H. Molecular initiating events of bisphenols on AR-mediated pathways provide guidelines for in silico screening and design of substitute compounds. Environmental Science & Technology Letter, 6(4): 205-210(2019)
3. Guo J, Shi W*, Chen Q, Deng D, Zhang X, Wei S, Yu N, Giesy J P, Yu H. Extended virtual screening strategies to link antiandrogenic activities and detected organic contaminants in soils. Environmental Science & Technology, 51(21): 12528−12536(2017)
4. Shi W, Yu N, Han Z, Wang S, Zhang X*, Wei S, Geisy J P, Yu H*. Influence of blooms of phytoplankton on concentrations of hydrophobic organic chemicals in sediments and snails in a hyper-eutrophic, freshwater lake. Water Research, 113: 22-31(2017)
5. Chen Q, Wang X, Shi W*, Yu H*, Zhang X, Geisy J P. Identification of thyroid hormone disruptors among HO-PBDEs: In vitro investigations and co-regulator involved simulations. Environmental Science & Technology, 50(22)：12429-12438(2016)
6. Qu C, Shi W*, Guo J, Fang B, Wang S, Giesy J P, Holm P E. China’s Soil Pollution Control: Choices and Challenges. Environmental Science & Technology, 50(24): 13181-13183(2016)
7. Hu X, Shi W*, Yu N, Jiang X, Wang S, Giesy J P, Zhang X, Wei S, Yu H*. Bioassay-directed identification of organic toxicants in water and sediment of Tai Lake, China. Water Research, 73(15): 231–241(2015)
8. Hu X, Shi W*, Wei S, Zhang X, Feng J, Hu G, Chen S, Giesy J P, Yu H*. Occurrence and potential causes of androgenic activities in source and drinking water in China. Environmental Science & Technology, 47 (18): 10591–10600(2013)
9. Wang X, Yang H, Hu X, Zhang X, Zhang Q, Jiang H, Shi W*, Yu H*. Effects of HO-/MeO-PBDEs on androgen receptor: In vitro investigation and helix 12-involved MD simulation. Environmental Science & Technology, 47 (2): 11802–11809 (2013)
10. Shi W, Hu X, Zhang F, Hu G, Hao Y, Zhang X, Liu H, Wei S, Wang X, Giesy J P, Yu H*. Occurrence of thyroid hormone activities in drinking water from eastern China: Contributions of phthalate esters. Environmental Science & Technology, 46 (3): 1811-1818 (2012)
Patents
1. Effect-oriented identification of targeted or non-targeted androgen disruptors. 2016.09.11, USA, 15/261985.
2. Screen methods for thyroid hormone disruptors based on co-regulator involved simulations. 2016.07.07, USA, 15203877.
3. A method for high-throughput screening of endocrine disruptors based on hierarchical warning structure. 2020.10.17, China, ZL 201811597767. 1.
4. A method for identifying key toxic substances in pesticide wastewater directed by Daphnia magna toxicity. 2016.04.13, China, ZL 201410236171.4.
5. Virtual screening of thyroid hormone disruptors based on nuclear receptor co regulatory factors and quantitative calculation method of their interference activity. 2018.08.24, China, ZL 201610201950.
6. Effect directed identification of target / non target androgen disruptors. 2018.07.03, China, ZL 2016102523544.
7. Virtual screening method of endocrine disruptors mediated by nuclear receptors based on molecular dynamics simulation. 2016.07.20, China, ZL 201310288617.3
8. Rapid identification of key pseudo / anti androgen interfering poisons in water samples. 2015.01.04, China, ZL 201310539205.2.
9. Identification of toxic chiral monomers in triazole fungicide wastewater, 2017.05.17, China, ZL 2015107337881.
10. Simultaneous purification and step-by-step separation of organic extracts from environmental media. 2012.10.10, China, ZL 200910232273.8.
