Location:
Hongxia Yu, Ph.D.
Professor
School of Environment
Nanjing University
Email: [email protected]
ORCID:
Education
1983 ~ 1987, Nanjing University, Bachelor in Department of Environmental Science
1989 ~ 1992, Nanjing University, Master in Department of Environmental Science and Engineering
2000 ~ 2002, Nanjing University, Ph.D. in School of Environment
Professional Experience
1987.6 ~ 1993.6, Nanjing University, Department of Environmental Science, Teaching Assistant
1993.6 ~ 1998.6, Nanjing University, Department of Environmental Science and Engineering, Lecturer
1998.1 ~ 1999.1, The University of Sheffield and National Water Research Center, Visiting Scholar
1998.6 ~ 2003.6, Nanjing University, School of Environment, Associate Professor
2002.2 ~2002.8, City University of Hong Kong, Department of Biochemistry, Research Fellow
2003.6 ~ Present, Nanjing University, School of Environment, Professor, Ph.D. Supervisor
2005.6 ~ 2009.6, Party Committee Secretary in School of Environment
2006.5 ~ 2009.6, Assistant Director of Department of Ecology and Environment of Jiangsu Province (serve a temporary position)
2009.6 ~ 2021.5, Deputy Director and Party member of Department of Ecology and Environment of Jiangsu Province
2021.6 ~ Present, Counsel Level 1 of Department of Ecology and Environment of Jiangsu Province
Research Interests
Environmental fates and ecological toxicology of persistent organic pollutants
Predictions of endocrine disrupting activities and corresponding mechanism based on chemical structure-activity relationships
Identification of key toxicants and monitoring technique in complex mixture
Risk assessment and management of chemicals
Academic Service
Currently a member of the Environmental Monitoring Technical Committee of the Ministry of Ecology and Environment, a member of the Environmental and Ecotoxicology Professional Committee of the Chinese Society of Toxicology, and a deputy director of the Management Committee of the National Engineering Research Center for Organic Pollution Control and Resource Reuse, editorial board member for "Chinese Journal of Applied Ecology" and "Asian Journal of Ecotoxicology".
Teaching
Selected Publications
Tan H.; Wang X.; Hong, H.; Benfenati E.; Giesy J. P.; Gini G. C.; Kusko R.; Zhang, X.; Yu H.; Shi W., Structures of Endocrine-Disrupting Chemicals Determine Binding to and Activation of the Estrogen Receptor alpha and Androgen Receptor. Environmental science & technology 2020, 54, (18), 11424- 11433.
Li Y.; Yu N.; Du L.; Shi W.; Yu H.; Song M.; Wei S., Transplacental Transfer of Per- and Polyfluoroalkyl Substances Identified in Paired Maternal and Cord Sera Using Suspect and Nontarget Screening. Environmental science & technology 2020, 54, (6), 3407-3416.
Yu N.; Wen H.; Wang X.; Yamazaki E.; Taniyasu S.; Yamashita N.; Yu, H.; Wei, S., Nontarget Discovery of Per- and Polyfluoroalkyl Substances in Atmospheric Particulate Matter and Gaseous Phase Using Cryogenic Air Sampler. Environmental science & technology, 2020, 54, (6), 3103-3113.
Ma Z.; Liu H.; Yu H., Triclosan Affects Ca2+ Regulatory Module and Musculature Development in Skeletal Myocyte during Early Life Stages of Zebrafish (Danio rerio). Environmental science & technology, 2019, 53, (20), 11988-11998.
Wang Y.; Yu N.; Zhu X.; Guo H.; Jiang J.; Wang X.; Shi W.; Wu J.; Yu H.; Wei Si., Suspect and Nontarget Screening of Per- and Polyfluoroalkyl Substances in Wastewater from a Fluorochemical Manufacturing Park. Environmental science & technology, 2018, 52, (19), 11007-11016.
Ma. Z.; Peng H.; Jin Y.; Zhang X.; Xie X.; Jian K.; Liu H.; Su G.; Tang S.; Yu H., Multigenerational Effects and Demographic Responses of Zebrafish (Danio rerio) Exposed to Organo-Bromine Compounds. Environmental science & technology, 2018, 52, (15), 8764-8773.
Shi W.; Yu N.; Jiang. X; Han Z.; Wang S.; Zhang X.; Wei S.; Giesy J. P.; Yu H.*, Influence of Blooms of Phytoplankton on Concentrations of Hydrophobic Organic Chemicals in Sediments and Snails in a Hyper-eutrophic, Freshwater Lake. Water Research 2017, 113, 22-31.
Chen Q.; Wang X.; Shi W.*; Yu H.*; Zhang X.; Giesy J. P., Identification of Thyroid Hormone Disruptors among HO-PBDEs: In Vitro Investigations and Coregulator Involved Simulations. Environmental science & technology 2016, 50, (22),12429-12438.
Yu, N.; Wang, X.; Zhang, B.; Yang, J.; Li, M.; Li, J.; Shi, W.; Wei, S.; Yu, H.*, Distribution of Perfluorooctane Sulfonate Isomers and Predicted Risk of Thyroid Hormonal Perturbation in Drinking Water. Water research 2015, 76, 171-180.
Hu, X.; Shi, W.; Yu, N.; Jiang, X.; Wang, S.; Giesy, J. P.; Zhang, X.; Wei, S.; Yu, H.*, Bioassay-directed Identification of Organic Toxicants in Water and Sediment of Tai Lake, China. Water research 2015, 73, 231-241.
Liu, H.; Tang, S.; Zheng, X.; Zhu, Y.; Ma, Z.; Liu, C.; Hecker, M.; Saunders, D. M.; Giesy, J. P.; Zhang, X., Yu, H.*, Bioaccumulation, Biotransformation, and Toxicity of BDE-47, 6-OH-BDE-47, and 6-MeO-BDE-47 in Early Life-stages of Zebrafish (Danio rerio). Environmental science & technology 2015, 49, (3), 1823-1833.
Li, J.; Yu, N.; Zhang, B.; Jin, L.; Li, M.; Hu, M.; Zhang, X.; Wei, S.; Yu, H.*, Occurrence of Organophosphate Flame Retardants in Drinking Water from China. Water research 2014, 54, 53-61.
Su, G.; Yu, H.*; Lam, M. H.; Giesy, J. P.; Zhang, X., Mechanisms of Toxicity of Hydroxylated Polybrominated Diphenyl Ethers (HO-PBDEs) Determined by Toxicogenomic Analysis with a Live Cell Array Coupled with Mutagenesis in Escherichia Coli. Environmental science & technology 2014, 48, (10), 5929-5937.
Wang, X.; Yang, H.; Hu, X.; Zhang, X.; Zhang, Q.; Jiang, H.; Shi, W.; Yu, H.*, Effects of HO-/MeO-PBDEs on Androgen Receptor: in Vitro investigation and Helix 12-involved MD Simulation. Environmental science & technology 2013, 47, (20), 11802-11809.
Hu, X.; Shi, W.; Wei, S.; Zhang, X.; Feng, J.; Hu, G.; Chen, S.; Giesy, J. P.; Yu, H.*, Occurrence and Potential Causes of Androgenic Activities in Source and Drinking Water in China. Environmental science & technology 2013, 47, (18), 10591-10600.
Yu, N.; Shi, W.; Zhang, B.; Su, G.; Feng, J.; Zhang, X.; Wei, S.; Yu, H.*, Occurrence of Perfluoroalkyl Acids Including Perfluorooctane Sulfonate Isomers in Huai River Basin and Taihu Lake in Jiangsu Province, China. Environmental science & technology 2013, 47, (2), 710-717.
Zheng, X.; Zhu, Y.; Liu, C.; Liu, H.; Giesy, J. P.; Hecker, M.; Lam, M. H.; Yu, H.*, Accumulation and Biotransformation of BDE-47 by Zebrafish Larvae and Teratogenicity and Expression of Genes Along the Hypothalamus–pituitary–thyroid axis. Environmental science & technology 2012, 46, (23), 12943-12951.
Su, G.; Xia, J.; Liu, H.; Lam, M. H.; Yu, H.*; Giesy, J. P.; Zhang, X.*, Dioxin-like Potency of HO-and MeO-analogues of PBDEs’ the Potential Risk through Consumption of Fish from Eastern China. Environmental science & technology 2012, 46, (19), 10781-10788.
Shi, W.; Hu, X.; Zhang, F.; Hu, G.; Hao, Y.; Zhang, X.; Liu, H.; Wei, S.; Wang, X.; Giesy, J. P., Yu, H.*, Occurrence of Thyroid Hormone Activities in Drinking Water from Eastern China: Contributions of Phthalate Esters. Environmental science & technology 2012, 46, (3), 1811-1818.
Su, G.; Zhang, X.; Liu, H.; Giesy, J. P.; Lam, M. H.; Lam, P. K.; Siddiqui, M. A.; Musarrat, J.; Al-Khedhairy, A.; Yu, H.*, Toxicogenomic Mechanisms of 6-HO-BDE-47, 6-MeO-BDE-47, and BDE-47 in E. coli. Environmental science & technology 2011, 46, (2), 1185-1191.
Patents
Screen Methods for Thyroid Hormone Disruptors Based on Co-regulator Involved Simulations. 2016.07.07. America. 15203877
Virtual Screening Methods for Thyroid Hormone Disruptors Based on Nuclear Receptor co-regulators and Quantitative Calculation of Their Activities. 2018.08.24. China. ZL 201610201950
Virtual Screening Method for Nuclear Receptor-mediated Endocrine Disrupting Substances Based on Molecular Dynamics Simulations, 2016.07.20. China. ZL 201310288617.3
A method for Quantitative Detection of Perfluorooctane Sulfonic Acid Isomers in Water Samples, 2015.04.01. China. 2012103688974
Rapid Identification of key pseudo/anti-androgenic Toxicants in Water Samples, 2015.01.14. China. 2013105392052
A Microinjection System and Microinjection Method and Application for the Toxicity Test of Organic Pollutants, 2014.12.10. China. 201210589394X
A method for Determining the Content of Tris(2,3-dibromopropyl) Phosphate in Water, 2014.10.01. China. 2012103770362
A High-performance Liquid Chromatography-time-of-flight Mass Spectrometry Method for Simultaneous Rapid Screening and Identification of Antihistamines in Water Samples, 2014.07.09. China. 2013102683376
An analytical Method of Solid Phase Extraction Coupled with Solid-phase Microextraction, 2013.10.16. China. 2009102642312
The method of Simultaneous Purification and Step-by-step Separation for Organic Extracts from Environmental Media, 2012.10.10. China. ZL 2009102322738
A Synchronous Purification and Extraction Method for Phenolic Substances, 2010.08.04. China. ZL 200810019214.8
Toxicity Identification Evaluation Program and Toxicity Calculation Software, 2009.11.15. China. 2010SR012680
A Modified Method of Solid-phase Microextraction, 2007.11.14. China . ZL200510095733.9
Awards
Research on the mechanism of environmental fates of emerging pollutants and structure-activity relationships, the Ministry of Education, the second prize of Natural Science Award for Scientific Research Outstanding Achievements in Colleges and Universities (2013, ranked first)
Research on mechanism and early warning of toxic effects of typical pollutants, the Ministry of Education, the first prize of Natural Science Award for Science and Technology of Colleges and Universities (2009, ranked fifth)
Research on genotoxicity early warning and carcinogenic risk control benchmarks for petrochemical PTA wastewater, China Petroleum and Chemical Industry Association, second prize for Scientific and Technological Progress (2008, ranked fifth)
Cross-subject constructing genetic engineering bacteria Fhhh to treat petrochemical wastewater biotechnology, Ministry of Ecology and Environment, third prize of Environmental Protection Science and Technology (2006, ranked fourth)
Research on the structure and mechanism of toxic organic matter, the second prize of Science and Technology Progress Award of the Ministry of Education (2002, ranked third)
The second prize of Jiangsu Provincial Education Commission for Excellent Curriculum Construction (2001, ranked second)
Research on the quantitative structure-property-activity of organic pollutants, the second prize of Science and Technology Progress Award of the State Education Commission (1997, ranked fifth)
The development of NDC-series photochemical reaction instrument, the first prize for Scientific and Technological Progress of Jiangsu Education Commission (1996, ranked fourth)
Quantitative structure-property-activity related research of organic pollutants, the second prize of Science and Technology Progress Award of the State Education Commission (1997, ranked fifth)
Selected as the "333" Second-level Young and Middle-aged Leading Talent in Science and Technology of Jiangsu Province in 2013
Rewarded as the "Eleventh Five-Year" National Advanced Individual in Environmental Science and Technology Work by the Ministry of Ecology and Environment in 2012
Selected as the Young and Middle-aged Academic Leader of the "Blue Project" in Jiangsu Province in 2004
Opportunities
Students major in Environmental Science or Environmental Safety and Health
